first_imgHurricane Cristobal passed hundreds of miles from Ocean City, but the storm generated big surf for one day on Aug. 28, 2014.The six-month hurricane season passed the halfway mark on Labor Day (Sept. 1) with only three tropical storms gathering enough strength to be named (sustained winds of at least 39 mph).A fourth, Dolly, became a tropical storm on Tuesday morning and is on a collision course with Mexico.Not since the 1994 hurricane season has it taken so long for the Atlantic Ocean to generate its fourth named storm. The other three (Arthur, Bertha and Cristobal) reached hurricane status, and each traveled north over the open water of the Atlantic Ocean.The first three months of the hurricane season made good on a forecast by the National Oceanic and Atmospheric Administration (NOAA) Climate Prediction Center for a “below normal” hurricane season with 7 to 12 named storms, 3 to 6 reaching hurricane status (sustained winds of at least 74 mph), and zero to 2 becoming major hurricanes (winds of at least 111 mph).Aside from Dolly, which will not affect the East Coast, there are no tropical systems expected to develop imminently as of Tuesday (Sept. 2).Hurricane season started on June 1 and continues through Nov. 30. Superstorm Sandy, whose record flooding came late in the season on Oct. 29, 2012, is still fresh in the minds of Ocean City residents and property owners.An Army Corps of Engineers beach replenishment project for the south end of Ocean City is scheduled to start in late November.Local surfers, who enjoy the storms that pass offshore, will have to wait for the next tropical swell. The video above shows the fading afternoon surf generated by Hurricane Cristobal. See more surf images from Cristobal.last_img read more

first_imgNadav Safran, a wide-ranging scholar of the politics of the Middle East, whose works charted the modern political history and foreign relations of Egypt, Israel, and Saudi Arabia throughout momentous years of turmoil, taught at Harvard from 1959 until his retirement as the Murray A. Albertson Professor of Middle Eastern Studies in 1990.Born in Cairo to Joseph and Jeanne (Abadi) Za’farani into a largely non-observant family of oriental Jewish lineage, Safran developed an interest in religion and Zionism after graduating from high school. He embarked on religious studies and moved to a kibbutz in Palestine in 1946, where he changed his first name from Clement to Nadav, meaning ‘generous’ in Hebrew, and his last name to Safran. Two years later he fought as a commando in Israel’s war of independence, becoming a lieutenant in the Israeli army after the 1949 armistice. Moving to the United States in 1950, he entered the then new Brandeis University from which he graduated in 1954. The following year he married Anna Balicka and they had three daughters: Nina, Abigail, and Elizabeth.After a year spent in Europe on a Sheldon Fellowship, Safran undertook graduate studies at Harvard, completing his doctorate in 1958. His dissertation, a history of political ideas in Egypt, which was one of the first in Middle Eastern studies to employ the broader social science concepts of Max Weber, was published in revised form in 1961 by Harvard University Press as Egypt in Search of Political Community: An Analysis of the Intellectual and Political Evolution of Egypt, 1804-1952.As befits the scholar of a region whose domestic politics is intimately bound up with international relations, Safran combined interests in both fields. In 1963 he published a broad survey of Israeli- American relations entitled The United States and Israel, followed in 1969 by a study of Arab-Israeli relations within a broader international setting, From War to War: The Arab-Israeli Confrontation 1948-1967. In 1978 he published Israel: The Embattled Ally, a wide-ranging account of the founding and development of that nation with an emphasis on its relations with the United States. A parallel study came out in 1985, entitled Saudi Arabia: The Ceaseless Quest for Security, which the New York Times Book Review called “the most comprehensive, informative and reliable account of Saudi foreign policy yet written.” It charts the conflicting imperatives and factional struggles over security policy in the Saudi Kingdom with analytic skill and the detail of a sweeping historical narrative that goes back to 1744.Safran was a prominent member of an intellectual generation that sought to integrate the study of the politics of the Middle East with the analytic issues of mainstream social science. His books and articles join deep historical learning to contemporary analytical ambitions. Safran’s scholarship was also marked by a deep sensitivity to the cultures and concerns on both sides of the Arab-Israeli conflict, whose histories and complexion he understood intimately. Although he had fought for Israel, he retained a deep affection for Egypt and revisiting that country later in life was a moving experience for him. In a field whose subject matter evokes strong views, Safran stood out as a figure who could understand all sides of the issues. He was a student of the Arab-Israeli conflict who would be welcome today: someone with a deep personal and scholarly understanding of the issues involved, from both sides of the conflict, who knew well the difficulties of finding common ground.In the Department of Government, Safran played an important role as a graduate teacher about the politics of a region with great international significance. In the training of doctoral students, he insisted that there was no substitute for a full command of the languages spoken by those whose circumstances scholars sought to understand. He argued that political scientists should sustain a life-long commitment to understanding a people’s context, including where on the map they are located and the effects wrought by the timing and sequence of events. His teaching embodied a concern not only for the impact of wars but also for the multifarious effects of local cultures. Safran worked closely with his doctoral students and remained in touch with many of them for years after their graduation.Nadav Safran was a person of great good humor and a delightful conversationalist, and his affable temperament served him well on many occasions, not least when he served as Director of Harvard’s Center for Middle Eastern Studies, whose activities he significantly enlarged. He resigned from that position in 1986 amidst controversy over a grant received from the CIA, but remained a faculty member in the Department of Government until 1990, where his intellectual engagements had long ranged well beyond the Middle East. In seminars, Safran would often cast a skeptical eye on the conventional wisdom spouted about other parts of the world. As a colleague, he lent a sympathetic ear to junior colleagues who welcomed him as an interlocutor.In his later years, Safran pursued longstanding interests in the arts, and he took up painting with a striking enthusiasm. At his death, he was survived by his three daughters, Nina, Abigail, and Elizabeth, and his former wife, Anna, as well as three brothers and two sisters living in Israel.Respectfully submitted,Edward L. KeenanE. Roger OwenRoy MottahedehPeter A. Hall, Chairlast_img read more

first_img To achieve prepandemic vaccines, researchers would have to ascertain the right dose and dose interval, determine how long priming lasts, and solve the puzzle of measuring primed immunity. Further, regulatory authorities would have to determine the trial design that could deliver those answers, the public discussion that would be necessary for prepandemic vaccines to be accepted, and the safety data that would need to be gathered once the vaccines went into use (see Bibliography: Goodman 2007). A number of the studies that have shown adjuvants may be able to stretch the vaccine supply also demonstrated a secondary benefit: The formulas protected not only against the H5N1 flu strain on which they were based, but against other H5N1 strains as well, a phenomenon called cross-reactive protection (see Bibliography: Nicholson 2001, Stephenson 2005, Govorkova 2006, Hehme 2007, Hoffenbach 2007). Most recently, the GlaxoSmithKline-backed team that described an acceptable immune response after two adjuvanted 3.8-microgram (mcg) doses found that three fourths of their subjects were protected not only against the clade 1 Vietnam virus on which the vaccine was based, but against a drifted clade 2 virus from Indonesia as well (see Bibliography: Leroux-Roels 2007). “I think priming should be done, but I am not sure how it should be done,” said Dr. John Wood, principal scientist in the division of virology at the United Kingdom’s National Institute for Biological Standards and Control. “What we don’t know is how low you can go to actually prime people. It may be that you can go much lower than where we can detect antibody. That is a regulatory headache, because you have to demonstrate that you are doing something, but there is a potential there” (see Bibliography: Wood 2007: author interview). At the moment, however, the science is thin. Much of the support for priming has come from animal studies (see Bibliography: Lipatov 2005, Govorkova 2006, Kreijtz 2007) or via computer modeling (see Bibliography: Longini 2005, Ferguson 2006, Germann 2006). A few small studies in humans have shown promising results. In one, serum from 15 volunteers who received three doses over 16 months of an adjuvanted vaccine based on a 1997 H5N3 isolate showed significant antibody response against H5N1 strains isolated years later (see Bibliography: Stephenson 2005). In another, 37 participants who had been given a baculovirus-grown, clade 3 H5 vaccine in 1998 were boosted with a single dose of the unadjuvanted 90-mcg Sanofi vaccine in 2005, and showed much higher antibody responses than participants who had not been primed but received one or two doses of the 90-mcg vaccine (see Bibliography: Treanor 2007: Immune responses). And researchers at a conference earlier this year reported that some of the participants in the phase 3 trial of the 90-mcg Sanofi vaccine were boosted with a third dose 6 months after their second dose and showed a significant rise in antibody levels that lasted for 6 months (see Bibliography: Zangwill 2007). A tough ethical problemBut the next logical step—that if vaccines can be formulated without waiting for a pandemic, they could be administered before a pandemic began—is a much tougher one to take, and policy makers are approaching it with great caution. The scientific, logistical, and especially ethical questions raised by prepandemic vaccination are grave. “Extraordinary threats call for consideration of innovative strategies that, in less-threatening circumstances, might be dismissed,” Bruce Gellin and Ben Schwartz of the Department of Health and Human Services’ National Vaccine Program Office wrote 2 years ago. “Although it has been assumed that pandemic vaccine cannot be stockpiled or that vaccination cannot occur before the start of a pandemic, might these approaches actually be possible? . . . Would receipt of a vaccine prepared before the pandemic be effective in providing some protection or in priming recipients so a single subsequent dose of vaccine would be protective?” (see Bibliography: Schwartz 2005). The danger demonstrated by both those campaigns, of causing adverse events while protecting against a disease that might never arise, has been noted in World Health Organization (WHO) policies as well. “Possible high-risk shortcuts in response to a potential emergency would be difficult to justify prior to the actual occurrence of the emergency,” the agency said after the June 2006 meeting of its Global Advisory Committee on Vaccine Safety. “Effectiveness of pandemic vaccines will not be known before the pandemic and possibly only after it is over” (see Bibliography: WHO 2006: Global Advisory Committee on Vaccine Safety, 6-7 June 2006). The prime-boost strategyThe most likely and biologically plausible use of prepandemic vaccination would be as the first half of a “prime-boost” series. People would still be given the two doses of vaccine necessary to provoke immunity in a naïve individual. But the doses would be based on different vaccine strains—the first an early best guess, the second tuned to the pandemic strain—and could be given not weeks but months or years apart if the science supported it. Yet the potential benefits of prepandemic vaccination are so alluring that governments have begun gingerly to lay groundwork for its consideration, despite the obvious difficulties of putting the idea into practice. The findings are not completely understood, though researchers agree that they make biological sense. Adjuvants stimulate the immune system in some manner that is broader than and different from the body’s reaction to the antigen packaged with them. The discovery that adjuvanted flu vaccines may invoke cross-reactivity has generated tremendous excitement—because that could allow production of at least partially protective vaccines well in advance of a pandemic’s beginning. Part 1: Flu research: a legacy of neglectPart 2: Vaccine production capacity falls far shortPart 3: H5N1 poses major immunologic challengesPart 4: The promise and problems of adjuvantsPart 5: What role for prepandemic vaccination?Part 6: Looking to novel vaccine technologiesPart 7: Time for a vaccine ‘Manhattan Project’?Bibliography Hurdles are manySo many steps separate those early results from an agreed-upon policy that would allow for prepandemic vaccines—in an annual flu shot or stockpiled until the WHO declares a pandemic imminent—that it is unrealistic to expect them to be created any time soon. The scientific questions alone are significant and novel. Any vaccination that took place before a pandemic was detected would offer uncertain amounts of both benefit and risk. The vaccine might be cross-protective against a future pandemic—but the lag time to the pandemic’s emergence might be so long that the vaccination would seem pointless. As well, the vaccine might cause a greater-than-expected rate of adverse events, causing both direct harm to recipients and indirect damage to government credibility—results that would be particularly difficult to tolerate if vaccination proved unnecessary because the pandemic did not arrive. Those risks are not theoretical: They have been demonstrated in the United States twice in recent history, in the abortive 2002 smallpox vaccination campaign and the 1976 swine-flu campaign (see Bibliography: Kotalik 2005), which has haunted US flu decision-making ever since. Editor’s note: This is the fifth in a seven-part series investigating the prospects for development of vaccines to head off the threat of an influenza pandemic posed by the H5N1 avian influenza virus. The series puts promising advances in vaccine technology in perspective by illuminating the formidable barriers to producing large amounts of an effective and widely usable vaccine in a short time frame. Part 4 examined the possibility of using adjuvants to stretch the supply of pandemic vaccines and the regulatory barriers to that strategy. Recognizing those hurdles, the European Centre for Disease Prevention and Control said in August that while it welcomes the development of prepandemic vaccines, it would not support administering them until a WHO declaration of pandemic phase 5 or 6, meaning significant human-to-human transmission is occurring or a pandemic is under way (see Bibliography: ECDC 2007: “Pre-pandemic” vaccines might offer protection but uncertainties remain). The pandemic vaccine puzzle Oct 31, 2007 (CIDRAP News) – Experiments with vaccine adjuvants have raised some hope of removing one of the great stumbling blocks to pandemic influenza preparedness: the impossibility of making a vaccine that protects against a pandemic virus before that virus actually emerges. last_img read more

first_imgAUCKLAND, New Zealand (CMC): Former West Indies cricketer, Franklyn Rose, has been deported from New Zealand, the country’s Immigration Department has confirmed. Rose, who played 19 Tests for the West Indies, was deported after living in New Zealand without a visa for four years. His legal representative, Ramya Sathyanathan, said a last-minute request to suspend the deportation on humanitarian grounds failed. The right-arm bowler has been in a New Zealand prison for the past five weeks after being detained. Sathyanathan says Rose suffered depression, which worsened as a result of his five-week detention at Mount Eden prison. Rose was originally granted a work visa when he was offered a position as coach for the University of Auckland Cricket club, but has not had a valid visa since 2012. He was told he would be deported in 2014, having worked for the Salvation Army and a number of Auckland Schools in the interim in a coaching role. The former Windies player was deported on a flight to Jamaica.last_img read more

first_imgWell-known Newtowncunningham man Con Holmes is going walkies again in his bare feet!This time Con is walking 11 kms from Letterkenny to Newtown on Friday, June 22nd at 5pm. Again Con is doing this in aid of NCDI & The Breast Unit at Letterkenny Hospital.Sponsor cards are availble from Kathleen at the NCDI office 074 91 56898 or by phoning Betty at 087 2905 946. If not there will be a bucket collection on the day.Con is partly raising funds for the Breast Unit in recognition of the work of the unit, Donegal Action Against Cancer and also the fact that we have four daughters and at present four grand-daughters.This walk is a great opportunity for folk to come along join in for a wee bit of the walk, do the whole thing or do what suits you on the day. People are invited to the walk you can keep your shoes on, off or whatever suits you.There will also be a wee cuppa tea & a piece at Coyle’s Bar & Restaurant in Newtowncunningham when Con arrives back there. CON BARES ALL TO WALK THE WALK FOR CHARITY! was last modified: June 2nd, 2012 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:bare-feetcancerCon Holmeslast_img read more

first_imgTyphoon Kammuri accelerates, gains strength en route to PH Lee logged only three minutes and 44 seconds in Game 2 in what could be his season-finale after his nagging knee injury recurred at the worst possible time for the Hotshots.READ: Meralco zaps lackluster Star, nears PBA semis sweepFEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSSEA Games: Philippines picks up 1st win in men’s water poloSPORTSMalditas save PH from shutout“It’s the old injury,” Lee told reporters. “I aggravated it last game. I actually just forced myself to play last game. I tested it but I couldn’t.”He has been bothered by the same knee injury since last year. It was also the reason why he was pulled out of Gilas Pilipinas last March and in May of 2016. BSP sees higher prices in November, but expects stronger peso, low rice costs to put up fight Brace for potentially devastating typhoon approaching PH – NDRRMC Lopetegui wants focus on soccer after Pique jeered by fans View comments Read Next LOOK: Loisa Andalio, Ronnie Alonte unwind in Amanpulo for 3rd anniversary LATEST STORIES The playoff schedule also didn’t help the 28-year-old’s health issues with teams playing every other day.READ: Top seed Meralco comes back to beat Star in semis opener“Our games have been in succession so our PT told me that this is expected to happen. There’s a slight meniscus tear,” said Lee, who scored 11 points in Game 1.Lee said his status is “day-to-day” and he offered no assurance on whether he’s going to be available in Game 3 on Thursday.“I didn’t practice yesterday (Monday). I just tried to play today,” he said. “It’s painful. I made a quick move in the first quarter and I felt something.”ADVERTISEMENTcenter_img Fire hits houses in Mandaluyong City Nonong Araneta re-elected as PFF president Trending Articles PLAY LIST 00:50Trending Articles00:50Trending Articles00:50Trending Articles01:37Protesters burn down Iran consulate in Najaf01:47Panelo casts doubts on Robredo’s drug war ‘discoveries’01:29Police teams find crossbows, bows in HK university01:35Panelo suggests discounted SEA Games tickets for students02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games CONTRIBUTED PHOTO/PBA IMAGESSTA. ROSA — Paul Lee slogged his way out of Santa Rosa Multipurpose Complex Tuesday night. His head was slightly down, his gloomy face barely seen as he wore a black cap tilted downward.Star is one game away from getting swept by Meralco, which looked every bit of a top-seeded team, and the Hotshots could likely be without their prized guard as they fight for survival starting Thursday.ADVERTISEMENT Fire hits houses in Mandaluyong City Frontrow holds fun run to raise funds for young cancer patients  Don’t miss out on the latest news and information. MOST READlast_img read more

first_imgVirat Kohli said there is no bigger challenge than a World Cup for a cricketer as he gears up to lead India in the mega event starting England in a few weeks. Kohli was part of India’s World Cup-winning side in 2011 and was a key member of the 2015 team which reached the World Cup semifinals Down Under.Virat Kohli has been in exceptional form with the bat over the last 3 years. In 2018, Kohli shattered several records in South Africa and led India to a historic ODI series win. Earlier this year, Virat Kohli led India to ODI series wins in Australia and New Zealand.Virat Kohli recently became the first cricketer to be awarded the top three ICC awards (Cricketer of the year, Test cricketer of the year and ODI cricketer of the year) in a single year.India have achieved a lot in ODIs over the last 1 year, especially away from home. But like every other cricketer, Virat Kohli is aware of the importance of the World Cup. He said this would be a very different World Cup for him. In 2011, he was one of the youngest members of the team while in 2015, a lot more was expected.’In 2011, I wasn’t involved in a lot of things’8 years after India lifted the World Cup in Mumbai, Virat Kohli will have his hands full as the side’s best batsman and captain.”This is going to be the tournament in which I will be involved in a lot of things. In 2011, I was not involved in a lot of things, was not involved in a lot of meetings, the pressures that come along. At this point in time it’s going to be different,” Virat Kohli told India Today in an exclusive interview.advertisement”Even in 2015, I wasn’t involved to an extent where I had to be part of everything that is going on. To understand the magnitude of a tournament like this from a captain’s point of view is a different ball game. When you play so much international cricket, after a while you need a bigger challenge and there’s nothing bigger than the World Cup,” he added.So far in an illustrious career, Virat Kohli has scored 10843 runs including 41 hundreds and 49 fifties in 227 ODIs. He will be key for India and he said will look to do as much as he can in the 2019 Cricket World Cup.”I will look to contribute as much as I can. Won’t say that I will look to do something different just because it’s a World Cup. Fortunately, I am in the mindset, I don’t have to pick myself up for a series, because I always have the same intensity and drive to take the team over the line,” Virat Kohli told India Today.”To make the team win, to contribute to the team’s cause are the pressure I enjoy. I don’t necessarily focus on things that are expected of me, because there are a lot of things that are controllable. Expectations are absolutely fine because people want me to do well. The main focus is to stay in the mindset how the team is playing and whether it is doing well or not,” Kohli said.Also See | Loyalty matters most: Virat Kohli recalls early support from MS DhoniAlso Read | Unfortunate to see so many people going after MS Dhoni: Virat Kohli to India TodayAlso Read | Virat Kohli on why Kuldeep and Chahal will be lethal at 2019 World CupAlso See:last_img read more

first_imgMan City plan Sterling extension to warn off Real Madridby Ansser Sadiqa month agoSend to a friendShare the loveRaheem Sterling is eyeing a move to Real Madrid in the summer, per journalist Alex Kay-Jelski.The reporter, who has very good sources at City and with Sterling’s camp, believes that Real are serious about signing the English winger.Sterling is only 24 and has emerged as one of the best and most consistent players in the Premier League.He has come on leaps and bounds since manager Pep Guardiola took over at the club, helping them to two Premier League titles in a row.While Real are serious in their interest and Sterling would fancy the move, the source also claims that City will offer him a bumper new deal to convince him that his future lies in Manchester.City would loathe to lose Sterling, given he is one of their most prolific attacking players. TagsTransfersAbout the authorAnsser SadiqShare the loveHave your saylast_img read more

first_imgCardale Jones swings and misses at a softball.Twitter/@STN_Sports Every year, NCAA member schools have to self-report dozens of violations, the vast majority of which are quite inane. Ohio State’s student newspaper The Lantern reports that the school reported 29 minor violations, six of which came from the football program. The most interesting of them centers on quarterback Cardale Jones’ attendance as a celebrity softball game hosted by Cleveland Browns star Joe Haden.Cardale Jones and Prime Time at Joe Haden’s Celebrity softball game pic.twitter.com/tYUaV2G0Gk— Mary Kay Cabot (@MaryKayCabot) June 6, 2015In one case, an OSU football player was told that he was neither permitted to participate in nor attend the Joe Haden Celebrity Charity Softball game in Cleveland on June 6. However, on the morning of the event he called his position coach and was told he could attend the event but not participate.Because the school had not provided written approval to attend, a violation had occurred. An OSU spokesman could not confirm the identity of the player, but redshirt junior quarterback Cardale Jones was documented to have attended the game.In response to the violation, a letter of education was provided to all football coaches and staff emphasizing the rules regarding promotional activities, as well as reviewed with football student-athletes.Braxton Miller’s Instagram photo promoting AdvoCare from the spring was also included in the report. It should be noted that there should not be an repercussions for minor offenses like these, but it is always interesting to look at the things that are deemed violations by the NCAA. Many of them are pretty ridiculous.[The Lantern via Eleven Warriors]last_img read more